Unconditioned unrelated donor bone marrow transplantation for IL7Rα- and Artemis-deficient SCID
نویسندگان
چکیده
منابع مشابه
B-cell recovery after stem cell transplantation of Artemis-deficient SCID requires elimination of autologous bone marrow precursor-B-cells.
Severe combined immunodeficiencies (SCID) are commonly fatal early in life. Adequate diagnosis and rapid institution of treatment, such as allogeneic stem cell transplantation (SCT), is essential. Several studies demonstrated that reconstitution of B-cell function after SCT is better in B-positive SCID than in B-negative SCID. We demonstrate that B-cell reconstitution in a B-negative SCID patie...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2017
ISSN: 0268-3369,1476-5365
DOI: 10.1038/bmt.2017.74